2009, discovery of a fresh phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings together DNA working with good-point out nanopores
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, Groningen scientists current the final results in their endeavours to help make labs more sustainable and provide strategies for other labs.
2007, first genuine-time detection of strand exchange in homologous recombination by RecA; discovery of a reduced persistence length of ends of microtubules; and solved the mechanism of biosensing with carbon nanotubes
2015, discovery that condensin is often a very flexible protein structure; and to start with detection of DNA knots employing nanopores
Case in point (three) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in grey, the rim from the pore is highlighted in pink, plus a 3D rendering from the movement in the DNA rod is displayed.
You're a Christian. If you can make this kind of synthetic mobile, would you be a single phase nearer to God, or would the position of God have diminished somewhat yet again?
Nanopores represent an elegant and versatile tool to evaluate one molecules. We investigate novel detection modes with solid-point out nanopores in addition to numerous methods to measure proteins with nanopores. Jobs encompass the subsequent:
2003, shown the primary biosensors created from a carbon nanotube; resolved the composition and system of DNA fix proteins; and discovery of a fresh method for fabricating solid-point out nanopores for DNA translocation
Dekker started off his investigation on single carbon nanotubes in 1993 when he build a whole new line of study to check electrical transport through one natural molecules concerning nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was achieved in a very collaboration With all the team of Nobel laureate Richard Smalley. STM and nanolithography tactics had been utilized to show that these nanotubes are quantum wires at The one-molecule degree, with superb Bodily Attributes.
[fourteen] In 2005 Dekker turned associated with Netherlands-large discussions about Clever Style, a motion that he has since Obviously distanced himself from. Dekker advocates that science and faith aren't in opposition but might be harmonized.
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Case in point (2) of bending configurations in ceesdekker 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in purple, along with a 3D rendering with the motion on the DNA rod is displayed.